SPEED UP SAFARI (TRY THESE GOODIES!)
Try this guide first:
http://guides.macrumors.com/Speed_up_Safari
Have you done these other basics, as well?
1. Empty your cache & History settings via the Safari menu
2. Trash your Icons Folder:
HD>Users>Home>YourName>Library>Safari -->Icons
Restart Safari and a new folder will be automatically regenerated.
(This folder saves favicons of all the sites you visit. Needs cleaning periodically -- or you can change that file's preferences to "Read Only"
rather than "Read & Write." This will keep it from growing in size.)
3. Launch Font Book and check all fonts for duplicates. A duplicated font will have a bullet beside the font family and you can resolve duplicates by selecting the font and at the menu bar, go to Edit > Resolve Duplicates.
Do this for each font with a bullet next to it.
Question: Do you have internet apps SpeedDownload, iGetter, PithHelmet, Acid Search, Safari Enhancer ? Or Norton or Virex? Sometimes non-apple internet apps need updating or uninstalling.
IF THIS DOES NOT WORK THEN GO FOR THE COMPLETE SAFARI OVERHAUL HERE @
http://docs.info.apple.com/article.html?artnum=107657